Targeted Antioxidant SystemTM (TAS-α)
TAS-α is a 3rd-generation combination of efficient sources of intracellular cysteine—rate limiting components used for intracellular reassembly of the tripeptide glutathione (GSH)  TAS-α includes staged antioxidant resources that are designed to simultaneously maintain: GSH’s antioxidant activity (refurbish GSSG to GSH); and GSH levels via reductions in the extracellular escape of GSSG. Intracellular GSH promotes erythrocyte (—10/1 ) flexibility which is required both for their flow though typically smaller diameter capillaries (—5-8″) and consequent oxygen and nutritional servicing of deeper and peripheral tissues.
TAS-α is a dietary supplement targeted at both maintaining intracellular glutathione (GSH) antioxidant levels and activity. Intracellular GSH levels — poorly transported through cell walls are largem established Intracellulatly fromäts constituent amino acids glutamate, glycine, and cysteine — the latter being “rate-limiting” and consequently a target for efficient supplementation by TAS-α. Subsequently, serving as an electron donor (as part of its intracellular roles) GSH is transformed into GSSG — which can readily pass though cell walls and may be lost into the extracellular media unless quickly refurbished by other antioxidant resources — the latter consequently also is a target of TAS-α. GSH functions in several systems within the body that assist with: (1) Detoxification of fatsoluble compounds, (2) Supporting amino-acid transport, (3) DNA synthesis and immune system augmentation; as well as, (4) Quenching of free radical and other reactive oxygen species (ROS). [e.g., This latter quenching activity — particularly with regard to promoting capillary microcirculation — is broadly important to:
- Performance (Physical and Mental),
- Stress(or)-Resistance, and
- Health/We11being [e.g., 2,3]
Excessive ROS — and lower levels of GSH — have long-been associated with the pathogenesis of a variety of diseases that in part include:
- Cancer [7,13]
- Cardiovascular diseases (e.g., atherosclerosis; hypertension)
- Diabetes Mellitus [2,3, 7,131
- Neurological disorders (e.g., Alzheimer’s & Parkinson’s diseases)
- Pulmonary diseases (e.g., Asthma, Acute-Respiratory-Distress-Syndrome/ARDS),
Chronic-Obstructive-Pulmonary-Disease/COPD) [ 1 ‘2‘6‘8‘9‘ 13]
- Rheumatoid Arthritis. • [e.g., 10,13]
- Viral Bacterial Infection/Reduced Immunity [e.g.,
Aging is strongly associated with several of the above diseases; hence, it is not surprising that both: (l) Excessive ROS, and lower levels of GSH, have been associated with accelerated aging; and (2) Targeted antioxidants — eg. TAS-a — identified as a means for intervention to enhance mental and physical performance, stress resistance as well as health/wellbeing.[e.g., 2-7,11]
Vitamin C(from Ascorbyl Palmitate) Vitamin C(Ascorbic Acid) Proprietary Blend: N-Acetyl Cysteine,R-Alpha Lipoic Acid, Glucosamine Sulfate, Other Ingredients: Gelatin capsule, Silica.
Take 1 capsule twice daily AM & PM as a dietary supplement or as Directed by your health care professional
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